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Custom Gene-Editing Therapies for Rare Diseases Could Win Faster Approvals Under FDA Draft Plan, Not Yet Final

The FDA's draft guidance could streamline approval of gene-editing therapies tailored to individual mutations, while families and experts weigh safety, affordability, evidence requirements, and access challenges.

HealthOpen page
Article

Namibia says ramping up Ebola preparedness at entry points

Windhoek: Namibia,following the spread of the Ebola disease across several countries, hasintensified disease surveillance and reinforced preparedness...

AfricaOpen page
Article

Is Gluten-Free Bread Better For You Than Regular Bread?

Even if you don't suffer from celiac disease or some other gluten sensitivity, you may wonder if gluten-free bread is better for you. One dietitian explains.

FoodOpen page
Article

Days of Our Lives Star Robert Kelker-Kelly’s Cause of Death Revealed After Sudden Symptoms

Day of Our Lives alum Robert Kelker-Kelly, who died Oct. 3 hours after experiencing pain in his chest and arm, was determined to have died of heart disease,…

HealthOpen page
Article

An Overlooked Immune Cell Killed The Deadliest Form of Lung Cancer in Lab Tests

Fewer than 7% survive this disease. ScienceAlert stories are written, fact-checked, and edited by humans, never generated by AI. Don't miss a story, subscribe here.

TechnologyOpen page
Article

Brett Myers, sheriff for 24 years, dies at 56

Pullman law enforcer succumbs to a rare neurological disease

HealthOpen page
Article

Climate shocks increase health risks for Africa's most vulnerable

Climate change is already reshaping Africa's health landscape, as rising temperatures, erratic rainfall, droughts, and floods worsen food insecurity, heighten infectious disease risks, and strain already fragile health…

AfricaOpen page
Article

Community spirometry hubs test 4,000 patients across Cardiff and Vale

More than 4,000 patients across Cardiff and the Vale of Glamorgan have already benefited from new community spirometry hubs designed to improve lung disease diagnosis.

CultureOpen page
Article

J&J’s Tremfya Sustains Crohn’s Remission Through 48 Weeks

SPRING HOUSE, PA — Johnson & Johnson (NYSE: JNJ) reported that its Crohn’s disease treatment Tremfya sustained or improved fistula remission through 48 weeks in a Phase 3…

World NewsOpen page
Article

Lifileucel Shows 50% Response Rate in Refractory UPS and Liposarcoma

Data presented at ESMO Congress 2026 show lifileucel met its feasibility end point in refractory sarcoma, with 80% disease control among 10 patients.

EntertainmentOpen page
Article

Multivalent pDNA vaccine prolongs BCG-mediated control of M. tuberculosis

Mycobacterium tuberculosis remains a leading cause of infectious disease-mediated death, with 10.8 million reported cases of active disease and 1.25 million deaths only in 2023. The Bacillus Calmette-Guerin…

HealthOpen page
Article

Annovis Targets 2027 Alzheimer’s Drug Data Readout

MALVERN, PA — Annovis Bio Inc. (NYSE: ANVS) will present updates on its experimental Alzheimer’s disease treatment buntanetap at a November medical conference in Boston as the Malvern-based…

HealthOpen page
Article

Patient CRM Modernization: Four Decisions Technology Can’t Make for You

Consider a daughter who signs up for disease information on behalf of her father. Weeks later, he enrolls in copay assistance and asks another website for updates. To…

HealthOpen page
Article

New cacao variety could help protect global chocolate supply from disease

Chocolate lovers may not realize it, but the future of one of the world's most popular foods is increasingly under pressure. Diseases, shifting weather patterns and other environmental…

World NewsOpen page
Article

Medicenna’s MDNA-209 extends survival in GVHD models

Medicenna Therapeutics Corp. has released new preclinical data for MDNA-209, a long-acting IL-2/IL-15 superantagonist that effectively blocks the overactive CD122/CD132 pathway responsible for autoimmune diseases. The results demonstrated…

ScienceOpen page
Article

ADX-038 shows sustained alternative complement inhibition

Researchers from Adarx Pharmaceuticals Inc. presented preclinical and early clinical data on agazisiran (ADX-038), a double-stranded, GalNAc-conjugated siRNA developed to reduce complement factor B (CFB) expression.

Middle EastOpen page
Article

MARY-1 improves kidney function in DKD and AKI models

The serotonin 5-HT2B receptor has been implicated in maladaptive responses to renal injury, including inflammatory and fibrotic signaling, making it a potential therapeutic target. Researchers from the University…

ScienceOpen page
Article

Spyre Therapeutics antibodies, alone and in combination, ameliorate IBD phenotype

Spyre Therapeutics Inc. has developed and presented data for a series of antibodies with extended half-life, and their combination, for the treatment of inflammatory bowel disease (IBD). These…

ScienceOpen page
Article

Why we’ll never have another Black Death

The death of a worker at a Russian plague lab was alarming, but the disease is extremely unlikely to become a worldwide problem as it has in the…

ScienceOpen page
Article

Nurse treating Ebola patient killed by machete-wielding mob after being accused of spreading deadly disease

A HERO nurse working to contain the spread of Ebola has been hacked to death by a machete-wielding mob of youths, officials have said. Another health worker was…

AfricaOpen page
Article

Uganda: Parents Urged to Vaccinate Children Against Polio

[Nile Post] Parents across Uganda have been urged to ensure their children receive all recommended polio vaccines as health stakeholders renew efforts to prevent the disease from returning…

HealthOpen page
Article

Large meta-analysis sheds new light on how SGLT2 inhibitors affect blood and iron parameters

Research led by internist-nephrologist Dr. Michele Eisenga shows that SGLT2 inhibitors, a class of drugs widely used to treat type 2 diabetes, heart failure and chronic kidney disease,…

ScienceOpen page
Article

South African Labs Strive for Africa’s Biopharma Sovereignty

Africa still imports 99% of its routine vaccines and 70–90% of its biopharmaceuticals. The Africa CDC warns this vulnerability could cost the continent up to $1.1 trillion in…

AfricaOpen page
Article

Ebola patient evacuated from Nigeria to Switzerland

A woman infected with the Ebola virus and her husband, a Swiss diplomat, were flown from Nigeria to hospitals in Switzerland on Monday, Swiss authorities said. The Ugandan-born…

AfricaOpen page

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